FTL anticorps (AA 38-165)

N° du produit ABIN6252862

L’anticorps Souris Monoclonal anti-FTL a été validé pour WB, IHC, IF et FACS. Il convient pour détecter FTL dans des échantillons de Humain.

Aperçu rapide pour FTL anticorps (AA 38-165) (ABIN6252862)

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FTL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: FTL-1386

Détail du produit anti-FTL anticorps

Épitope: AA 38-165

Purification: Protein G affinity chromatography

Immunogène: Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin Light Chain antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Western blot: 0.1-0.2 μg/mL

Flow Cytometry: 0.1-0.2 μg/10^6 cells

IF: 0.1-0.2 μg/mL

IHC (FFPE): 0.1-0.2 μg/mL for 30 min at RT

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ferritin Light Chain antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur FTL

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: FTL1

Sujet: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

ID gène: 2512

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis