GP2 anticorps (AA 35-179)

N° du produit ABIN6252885

Cet anticorps Souris Monoclonal détecte spécifiquement GP2 dans IHC (p), FACS et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GP2 anticorps (AA 35-179) (ABIN6252885)

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GP2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: GP2-1712

Détail du produit anti-GP2 anticorps

Épitope: AA 35-179

Specificité: Does not react with Mouse

Purification: Protein G affinity chromatography

Immunogène: A partial human recombinant protein corresponding to amino acids 35-179 was used as the immunogen for the GP2 antibody.

Isotype: IgG2b lambda

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

IHC (FFPE): 1-2 μg/mL for 30 min at RT

Optimal dilution of the GP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur GP2

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Autre désignation: Glycoprotein 2

Sujet: GP2 (Glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.

ID gène: 2813

UniProt: P55259