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CD16 anticorps

CD16 Reactivité: Humain FACS, ICC Hôte: Souris Monoclonal B-E16 unconjugated

N° du produit ABIN6253847

Fiche de données

Antigène Voir toutes CD16 Anticorps

CD16
Reactivité
143

26

21

21

21

9

8

8

8

4

2

2

2

2

2

2

2

1

1

1
Humain
Hôte
127

29

14

1
Souris
Anticorps secondaires appropriés
Clonalité
143

26

1
Monoclonal
Conjugué
58

19

13

13

9

7

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD16 est non-conjugé
Application
136

31

31

26

24

23

22

20

5

5

4

3

3

3

2

2

2

1

1

1
Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificité

B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]

Pureté

PURE

Clone

B-E16

Isotype

IgG2a

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CD16 Reactivité: Humain FACS, WB, IHC, ELISA, ICC, Neut Hôte: Souris Monoclonal 2G10A9 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivité: Humain, Non-Human Primate FACS, IP, Func, IHC (fro) Hôte: Souris Monoclonal 3G8 unconjugated

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anti-CD16 (CD16) antibody
CD16 Reactivité: Humain FACS Hôte: Souris Monoclonal GRM1 unconjugated

Indications d'application

immunohistochemistry on cytospots, immunohistochemistry on frozen tissue

Restrictions

For Research Use only
Format

Liquid

Stock

4 °C
Antigène

CD16

Autre désignation

CD16 (CD16 Produits)

Synonymes

anticorps Fcgr3, anticorps Fcgr3a, anticorps CD16, anticorps FCGR3, anticorps FCGR3@, anticorps CD16b, anticorps FCG3, anticorps FCR-10, anticorps FCRIII, anticorps FCRIIIb, anticorps FcRIII, anticorps Fc fragment of IgG, low affinity IIa, receptor, anticorps Fc fragment of IgG, low affinity IIIa, receptor (CD16a), anticorps Fc fragment of IgG receptor IIIb, anticorps Fc fragment of IgG receptor IIIa, anticorps Fc receptor, IgG, low affinity III, anticorps Fc-gamma RIII, anticorps Fcgr2a, anticorps FCGR3A, anticorps FCGR3B, anticorps Fcgr3, anticorps FCGR3

Sujet

Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process