CD16 anticorps (PE)
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- Antigène Voir toutes CD16 Anticorps
- CD16
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD16 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Specificité
- B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]
- Clone
- B-E16
- Isotype
- IgG2a
- Top Product
- Discover our top product CD16 Anticorps primaire
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- Indications d'application
- immunohistochemistry on cytospots, immunohistochemistry on frozen tissue
- Restrictions
- For Research Use only
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- Format
- Liquid
- Stock
- 4 °C
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- Antigène
- CD16
- Autre désignation
- CD16 (CD16 Produits)
- Synonymes
- anticorps Fcgr3, anticorps Fcgr3a, anticorps CD16, anticorps FCGR3, anticorps FCGR3@, anticorps CD16b, anticorps FCG3, anticorps FCR-10, anticorps FCRIII, anticorps FCRIIIb, anticorps FcRIII, anticorps Fc fragment of IgG, low affinity IIa, receptor, anticorps Fc fragment of IgG, low affinity IIIa, receptor (CD16a), anticorps Fc fragment of IgG receptor IIIb, anticorps Fc fragment of IgG receptor IIIa, anticorps Fc receptor, IgG, low affinity III, anticorps Fc-gamma RIII, anticorps Fcgr2a, anticorps FCGR3A, anticorps FCGR3B, anticorps Fcgr3, anticorps FCGR3
- Sujet
- Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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