MECP2 anticorps (pSer421)
Aperçu rapide pour MECP2 anticorps (pSer421) (ABIN6254071)
Antigène
Voir toutes MECP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer421
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Specificité
- Specific for endogenous levels of the ~55 kDa truncated MeCP2 protein phosphorylated at Ser421. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.
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Réactivité croisée
- Souris, Rat
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Homologie
- human, non-human primate
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Attributs du produit
- Our MeCP2 (Ser421) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects MeCP2 (Ser421) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
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Purification
- Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.
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Immunogène
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser421 of mouse MeCP2, conjugated to keyhole limpet hemocyanin (KLH).
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Isotype
- IgG
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Indications d'application
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Dilution Range: WB Brain: 1:1000
Dilution Range: WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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Stock
- -20 °C
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Stockage commentaire
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
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Date de péremption
- 12 months
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: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." dans: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).
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: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." dans: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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Autre désignation
- MECP2
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Sujet
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Synonyms: AUTSX 3 antibody, AUTSX3 antibody, DKFZp686A24160 antibody, Mbd 5 antibody, Mbd5 antibody, MECP 2 antibody, MeCP 2 protein antibody, MeCP-2 protein antibody, Mecp2 antibody, MECP2_HUMAN antibody, Methyl CpG binding protein 2 (Rett syndrome) antibody, Methyl CpG binding protein 2 antibody, Methyl-CpG-binding protein 2 antibody, MRX 16 antibody, MRX 79 antibody, MRX16 antibody, MRX79 antibody, MRXS 13 antibody, MRXS13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, WBP 10 antibody, WBP10 antibody
Description Logic: Our MeCP2 (Ser421) rabbit polyclonal phosphospecific primary antibody is produced . It detects MeCP2 (Ser421) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
Gene Name Alternatives: MECP2
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Poids moléculaire
- 55 kDa
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ID gène
- 17257
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UniProt
- Q9Z2D6
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Pathways
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
Antigène
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