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MECP2 anticorps (pSer421)

Cet anticorps anti-MECP2 est un anticorps Lapin Polyclonal détectant MECP2 dans WB et ELISA. Adapté pour Souris. Ce Primary Antibody a été cité dans 1 publication.
N° du produit ABIN6254071

Aperçu rapide pour MECP2 anticorps (pSer421) (ABIN6254071)

Antigène

Voir toutes MECP2 Anticorps
MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reactivité

  • 105
  • 40
  • 31
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Souris

Hôte

  • 99
  • 10
  • 2
  • 1
Lapin

Clonalité

  • 102
  • 10
Polyclonal

Conjugué

  • 71
  • 9
  • 7
  • 7
  • 6
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MECP2 est non-conjugé

Application

  • 82
  • 66
  • 40
  • 26
  • 11
  • 11
  • 10
  • 9
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • Épitope

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    • 11
    • 8
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    • 3
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    • 3
    • 3
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    pSer421

    Specificité

    Specific for endogenous levels of the ~55 kDa truncated MeCP2 protein phosphorylated at Ser421. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

     Réactivité croisée

    Souris, Rat

    Homologie

    human, non-human primate

    Attributs du produit

    Our MeCP2 (Ser421) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects MeCP2 (Ser421) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

    Purification

    Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

    Immunogène

    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser421 of mouse MeCP2, conjugated to keyhole limpet hemocyanin (KLH).

    Isotype

    IgG
  • Indications d'application

    Dilution Range: WB Brain: 1:1000

    Dilution Range: WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    Stock

    -20 °C

    Stockage commentaire

    Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

    Date de péremption

    12 months
  • Buck, ONeill, Stitzel et al.: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." dans: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).

  • Antigène

    MECP2 (Methyl CpG Binding Protein 2 (MECP2))

    Autre désignation

    MECP2

    Sujet

    Synonyms: AUTSX 3 antibody, AUTSX3 antibody, DKFZp686A24160 antibody, Mbd 5 antibody, Mbd5 antibody, MECP 2 antibody, MeCP 2 protein antibody, MeCP-2 protein antibody, Mecp2 antibody, MECP2_HUMAN antibody, Methyl CpG binding protein 2 (Rett syndrome) antibody, Methyl CpG binding protein 2 antibody, Methyl-CpG-binding protein 2 antibody, MRX 16 antibody, MRX 79 antibody, MRX16 antibody, MRX79 antibody, MRXS 13 antibody, MRXS13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, WBP 10 antibody, WBP10 antibody

    Description Logic: Our MeCP2 (Ser421) rabbit polyclonal phosphospecific primary antibody is produced . It detects MeCP2 (Ser421) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

    Gene Name Alternatives: MECP2

    Poids moléculaire

    55 kDa

    ID gène

    17257

    UniProt

    Q9Z2D6

    Pathways

    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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