Ataxin 3 anticorps (AA 120-250)

N° du produit ABIN6254159

L’anticorps anti-Ataxin 3 Polyclonal Chèvre est utilisé pour la détection de Ataxin 3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Mouton, Cheval, Lapin, Cobaye, Chien, Singe, Porc, Cat, Poulet, Âne, Chévre, Hamster et Avian. Il a été validé pour WB.

Aperçu rapide pour Ataxin 3 anticorps (AA 120-250) (ABIN6254159)

Antigène: Ataxin 3 (ATXN3)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Cheval, Lapin, Cobaye, Chien, Singe, Porc, Cat, Poulet, Âne, Chévre, Hamster, Avian

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Ataxin 3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Ataxin 3 anticorps

Épitope: AA 120-250

Fonction: Anti-ATXN3

Séquence: KEHWFTVRKL GKQWFNLNSL LTGPELISDT YLALFLAQLQ QEGYSIFVVK GDLPDCEADQ LLQMIRVQQM HRPKLIGEEL AQLKEQRVHK TDLERVLEAN DGSGMLDEDE EDLQRALALS RQEIDMEDEE ADL

Specificité: Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot. This Ab is similar to AB0089.

Attributs du produit: Ataxin 3

Purification: Epitope affinity purified

Immunogène: Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.

Isotype: IgG

Information d'application

Indications d'application: WB:1:250-1:2,000

Restrictions: For Research Use only

Stockage

Buffer: preservatives. Glycerol and azide FREE.

Agent conservateur: Azide free

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Détails sur Ataxin 3

Antigène: Ataxin 3 (ATXN3)

Autre désignation: ATXN3

Sujet:

Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.

AT3, ATX3, ataxin-3, ataxin 3 variant h, autosomal dominant ataxin 3, ataxin 3 variant m, ataxin 3 variant ref, JOS, josephin, Machado-Joseph, Machado-Joseph disease protein 1, MJD, MJD1, SCA3, spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, spinocerebellar ataxia type 3 protein antibody.