Huntingtin anticorps (AA 85-200)

N° du produit ABIN6254174

Il existe 1 publication pour ce produit. L’anticorps anti-Huntingtin Polyclonal Chèvre est utilisé pour la détection de Huntingtin dans des échantillons de Humain, Rat, Souris, Lapin, Singe, Cheval, Chien, Mouton, Porc, Hamster, Cobaye, Chévre, Âne, Boeuf (Vache), Poulet, Cat et Avian. Il a été validé pour WB, IF, IHC (p) et IHC (fro).

Aperçu rapide pour Huntingtin anticorps (AA 85-200) (ABIN6254174)

Antigène: Huntingtin (HTT)

Reactivité: Humain, Rat, Souris, Lapin, Singe, Cheval, Chien, Mouton, Porc, Hamster, Cobaye, Chévre, Âne, Boeuf (Vache), Poulet, Cat, Avian

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Huntingtin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Huntingtin anticorps

Épitope: AA 85-200

Fonction: Anti-HTT

Séquence: PLHRPKKELS ATKKDRVNHC LTICENIVAQ SVRNSPEFQK LLGIAMELFL LCSDDAESDV RMVADECLNK VIKALMDSNL PRLQLELYKE IKKNGAPRSL RAALWRFAEL

Specificité: Reacts huntingtin protein, amino acids 85-200. The antibody recognizes wild type and mutant huntingtin.

Attributs du produit: Huntingtin

Purification: Epitope affinity purified

Immunogène: Purified recombinant peptide derived from within residues 85 to 200 aa of human HTT produced in E. coli

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:2,000, IF:1:500-1:2,000, IHC-P:1:500-1:2,000, IHC-F:1:500-1:2,000

Restrictions: For Research Use only

Stockage

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Références pour anticorps anti-Huntingtin (ABIN6254174)

Meunier, Merienne, Jollé, Déglon, Pellerin: "Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease." dans: Glia, Vol. 64, Issue 11, pp. 1841-56, (2018) (PubMed).

Détails sur Huntingtin

Antigène: Huntingtin (HTT)

Autre désignation: HTT

Sujet:

Huntingtin is a protein linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons.

HD, HTT and IT15 antibody.

Pathways: Signalisation PI3K-Akt, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport