Histone H4 anticorps (acLys5)

N° du produit ABIN6254903

Cet anticorps Lapin Polyclonal détecte spécifiquement Histone H4 dans WB, IHC, IF, ELISA et ICC. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour Histone H4 anticorps (acLys5) (ABIN6254903)

Antigène: Histone H4

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-Histone H4 anticorps

Épitope: acLys5

Specificité: Acetyl-Histone H4 (Lys5) Antibody detects endogenous levels of Acetyl-Histone H4 only when phosphorylated at Lys5

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Immunogen affinity purified

Immunogène: A synthesized peptide derived from human Acetyl-Histone H4 around the phosphorylation site of Lys5

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Références pour anticorps anti-Histone H4 (ABIN6254903)

Hu, Chang, Yan, Rong, Yang, Cheng, Gu, Yao, Hou, Mo, Zhao, Chen, Dinlin, Wang, Fang: "(-)-Epigallocatechin-3-gallate induces cancer cell apoptosis via acetylation of amyloid precursor protein." dans: Medical oncology (Northwood, London, England), Vol. 32, Issue 1, pp. 390, (2016) (PubMed).

Détails sur Histone H4

Antigène: Histone H4

Sujet:

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4

Poids moléculaire: 11kDa

ID gène: 121, 504, 554

UniProt: P62805