KLF4 anticorps (pSer254)

N° du produit ABIN6255133

Cet anticorps anti-KLF4 Polyclonal Lapin (ABIN6255133) détecte spécifiquement KLF4 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KLF4 anticorps (pSer254) (ABIN6255133)

Antigène: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-KLF4 anticorps

Épitope: pSer254

Specificité: Phospho-KLF4(Ser254) Antibody detects endogenous levels of KLF4.

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human KLF4 around the phosphorylation site of Ser254.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur KLF4

Antigène: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Autre désignation: KLF4

Sujet:

Description: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Gene: KLF4

Poids moléculaire: 62kDa

ID gène: 9314

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance