ATG13 anticorps (pSer355)
Aperçu rapide pour ATG13 anticorps (pSer355) (ABIN6255252)
Antigène
Voir toutes ATG13 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer355
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Specificité
- Phospho-Atg13 (Ser355) Antibody detects endogenous levels of Atg13.
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Réactivité croisée
- Humain, Souris, Rat (Rattus)
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Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogène
- A synthesized peptide derived from human Atg13 around the phosphorylation site of Ser355.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
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Date de péremption
- 12 months
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- ATG13 (Autophagy Related 13 (ATG13))
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Autre désignation
- Atg13
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Sujet
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Description: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Gene: ATG13
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Poids moléculaire
- 72kDa
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ID gène
- 9776
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UniProt
- O75143
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Pathways
- Signalisation PI3K-Akt, Autophagy
Antigène
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