EEF2K anticorps (pSer366)
Aperçu rapide pour EEF2K anticorps (pSer366) (ABIN6255261)
Antigène
Voir toutes EEF2K AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer366
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Specificité
- Phospho-eEF2k (Ser366) Antibody detects endogenous levels of eEF2k.
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Réactivité croisée
- Humain, Souris
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Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogène
- A synthesized peptide derived from human eEF2k around the phosphorylation site of Ser366.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
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Date de péremption
- 12 months
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- EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
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Autre désignation
- eEF2k
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Sujet
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Description: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
Gene: EEF2K
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Poids moléculaire
- 105kDa
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ID gène
- 29904
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UniProt
- O00418
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Pathways
- AMPK Signaling
Antigène
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