CaMK2 alpha/beta/delta anticorps (pThr305)

N° du produit ABIN6255659

Détail du produit anti-CaMK2 alpha/beta/delta anticorps

Antigène: CaMK2 alpha/beta/delta

Épitope: pThr305

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CaMK2 alpha/beta/delta est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: Phospho-CaMK2 alpha/ beta/ delta (Thr305) Antibody detects endogenous levels of CaMK2 alpha/ beta/ delta only when phosphorylated at Threonine 305

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human CaMK2 alpha/ beta/ delta around the phosphorylation site of Threonine 305

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur CaMK2 alpha/beta/delta

Antigène: CaMK2 alpha/beta/delta

Autre désignation: CaMK2 alpha/ beta/ delta (CaMK2 alpha/beta/delta Produits)

Sujet:

Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

Gene: CAMK2A

Poids moléculaire: 54kDa

ID gène: 815

UniProt: Q9UQM7, Q13554, Q13557