Synaptotagmin anticorps (pThr202)

N° du produit ABIN6256502

Cet anticorps Lapin Polyclonal détecte spécifiquement Synaptotagmin dans WB, IHC, ELISA, IF et ICC. Il présente une réactivité envers Rat, Souris et Humain.

Aperçu rapide pour Synaptotagmin anticorps (pThr202) (ABIN6256502)

Antigène: Synaptotagmin (SYT)

Reactivité: Rat, Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Synaptotagmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Synaptotagmin anticorps

Épitope: pThr202

Specificité: Phospho-Synaptotagmin (Thr202) Antibody detects endogenous levels of Synaptotagmin only when phosphorylated at Threonine 202

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Threonine 202

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur Synaptotagmin

Antigène: Synaptotagmin (SYT)

Autre désignation: Synaptotagmin

Sujet:

Description: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Gene: SYT1

Poids moléculaire: 60kDa

ID gène: 6857

UniProt: P21579, Q8N9I0