SYT1/2 anticorps (pThr202)

N° du produit ABIN6256502

Cet anticorps Lapin Polyclonal détecte spécifiquement SYT1/2 dans WB, IHC, IF et ICC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SYT1/2 anticorps (pThr202) (ABIN6256502)

Antigène: SYT1/2 (Synaptotagmin 1/2 (SYT1/2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYT1/2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-SYT1/2 anticorps

Épitope: pThr202

Fonction: Phospho-Synaptotagmin 1/2 (Thr202) Antibody

Specificité: Phospho-Synaptotagmin (Thr202) Antibody detects endogenous levels of Synaptotagmin only when phosphorylated at Threonine 202

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Synaptotagmin 1/2 around the phosphorylation site of Thr202.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SYT1/2

Antigène: SYT1/2 (Synaptotagmin 1/2 (SYT1/2))

Autre désignation: Synaptotagmin 1/2

Sujet:

Description: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Gene: SYT1

Poids moléculaire: 60kDa

ID gène: 6857

UniProt: P21579