Coxsackie Adenovirus Receptor anticorps (N-Term)

N° du produit ABIN6256932

Détail du produit anti-Coxsackie Adenovirus Receptor anticorps

Antigène: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coxsackie Adenovirus Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: CXADR Antibody detects endogenous levels of total CXADR.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CXADR, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Coxsackie Adenovirus Receptor

Antigène: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Autre désignation: CXADR (CXADR Produits)

Synonymes: anticorps CAR, anticorps CAR4/6, anticorps HCAR, anticorps Car1, anticorps car, anticorps cb331, anticorps fb76g12, anticorps wu:fb76g12, anticorps 2610206D03Rik, anticorps AU016810, anticorps AW553441, anticorps MCAR, anticorps MCVADR, anticorps hcar, anticorps xCAR, anticorps CXADR, anticorps CXADR, Ig-like cell adhesion molecule, anticorps coxsackie virus and adenovirus receptor, anticorps CXADR, Ig-like cell adhesion molecule L homeolog, anticorps CXADR, anticorps Cxadr, anticorps cxadr, anticorps cxadr.L

Sujet:

Description: Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Gene: CXADR

Poids moléculaire: 40 kDa

ID gène: 1525

UniProt: P78310

Pathways: Cell-Cell Junction Organization