ADCY5/6 anticorps (Internal Region)
Aperçu rapide pour ADCY5/6 anticorps (Internal Region) (ABIN6257031)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Fonction
- ADCY5/6 Antibody
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Specificité
- ADCY5/6 Antibody detects endogenous levels of total ADCY5/6.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human ADCY5/6, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- ADCY5/6 (Adenylate Cyclase 5/6 (ADCY5/6))
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Autre désignation
- ADCY5/6
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Sujet
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Description: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642, PubMed:26206488, PubMed:24700542). Mediates signaling downstream of ADRB1 (PubMed:24700542). Regulates the increase of free cytosolic Ca2+ in response to increased blood glucose levels and contributes to the regulation of Ca2+-dependent insulin secretion (PubMed:24740569).
Gene: ADCY5
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Poids moléculaire
- 138 kDa
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ID gène
- 111, 112
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UniProt
- O95622
Antigène
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