MAGEC2 anticorps (Internal Region)

N° du produit ABIN6257317

Détail du produit anti-MAGEC2 anticorps

Antigène: MAGEC2 (Melanoma Antigen Family C, 2 (MAGEC2))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGEC2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: MAGEC2 Antibody detects endogenous levels of total MAGEC2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MAGEC2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MAGEC2

Antigène: MAGEC2 (Melanoma Antigen Family C, 2 (MAGEC2))

Autre désignation: MAGEC2 (MAGEC2 Produits)

Synonymes: anticorps CT10, anticorps HCA587, anticorps MAGEE1, anticorps MAGEC2, anticorps MAGE family member C2, anticorps melanoma antigen family C, 2, anticorps MAGEC2, anticorps Magec2

Sujet:

Description: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.

Gene: MAGEC2

Poids moléculaire: 41 kDa

ID gène: 51438

UniProt: Q9UBF1