PAK1IP1 anticorps (C-Term)

N° du produit ABIN6257409

L’anticorps Lapin Polyclonal anti-PAK1IP1 a été validé pour WB, ELISA, IF, IHC et ICC. Il convient pour détecter PAK1IP1 dans des échantillons de Humain et Souris.

Aperçu rapide pour PAK1IP1 anticorps (C-Term) (ABIN6257409)

Antigène: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK1IP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Détail du produit anti-PAK1IP1 anticorps

Épitope: C-Term

Specificité: PAK1IP1 Antibody detects endogenous levels of total PAK1IP1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PAK1IP1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur PAK1IP1

Antigène: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Autre désignation: PAK1IP1

Sujet:

Description: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868).

Gene: PAK1IP1

Poids moléculaire: ?48 kDa

ID gène: 55003

UniProt: Q9NWT1

Pathways: Telomere Maintenance