SRY anticorps (Internal Region)

N° du produit ABIN6257506

Détail du produit anti-SRY anticorps

Antigène: SRY (Sex Determining Region Y (SRY))

Épitope: Internal Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRY est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: SRY Antibody detects endogenous levels of total SRY.

Homologie: Pig,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SRY, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SRY

Antigène: SRY (Sex Determining Region Y (SRY))

Autre désignation: SRY (SRY Produits)

Synonymes: anticorps SRXX1, anticorps SRXY1, anticorps TDF, anticorps TDY, anticorps SRYGENE, anticorps Sry1, anticorps Sry3BI, anticorps Tdf, anticorps Tdy, anticorps SRY, anticorps sex determining region Y, anticorps sex determining region of Chr Y, anticorps SRY, anticorps Sry

Sujet:

Description: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.

Gene: SRY

Poids moléculaire: 37 kDa

ID gène: 6736

UniProt: Q05066