TEAD3 anticorps (Internal Region)

N° du produit ABIN6257529

Détail du produit anti-TEAD3 anticorps

Antigène: TEAD3 (TEA Domain Family Member 3 (TEAD3))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEAD3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TEAD3 Antibody detects endogenous levels of total TEAD3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TEAD3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TEAD3

Antigène: TEAD3 (TEA Domain Family Member 3 (TEAD3))

Autre désignation: TEAD3 (TEAD3 Produits)

Synonymes: anticorps DTEF-1, anticorps TEF-5, anticorps ETFR-1, anticorps TEAD-3, anticorps TEAD5, anticorps TEF5, anticorps Tcf13r2, anticorps cb882, anticorps tead3, anticorps TEA domain transcription factor 3, anticorps TEA domain family member 3, anticorps TEA domain family member 3 a, anticorps tubby like protein 1, anticorps TEAD3, anticorps Tead3, anticorps tead3a, anticorps TULP1

Sujet:

Description: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.

Gene: TEAD3

Poids moléculaire: 49 kDa

ID gène: 7005

UniProt: Q99594

Pathways: Regulation of Lipid Metabolism by PPARalpha