LMTK3 anticorps
Aperçu rapide pour LMTK3 anticorps (ABIN6257613)
Antigène
Voir toutes LMTK3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- LMTK3 Antibody detects endogenous levels of total LMTK3
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Réactivité croisée
- Humain, Souris
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide
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Isotype
- IgG
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Indications d'application
- WB 1:500~1:1000, IF/ICC 1:100-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
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Date de péremption
- 12 months
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- LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))
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Autre désignation
- LMTK3
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Sujet
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Description: Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).
Gene: LMTK3
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Poids moléculaire
- 40 kDa
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UniProt
- Q96Q04
Antigène
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