CysLTR1 anticorps (Internal Region)
Aperçu rapide pour CysLTR1 anticorps (Internal Region) (ABIN6257718)
Antigène
Voir toutes CysLTR1 (CYSLTR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- CLTR1 Antibody detects endogenous levels of total CLTR1.
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Homologie
- Rabbit
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human CLTR1, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))
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Autre désignation
- CYSLTR1
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Sujet
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Description: Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Gene: CYSLTR1
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Poids moléculaire
- 38 kDa
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ID gène
- 10800
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UniProt
- Q9Y271
Antigène
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