TLK1 anticorps (C-Term)

N° du produit ABIN6257779

Cet anticorps anti-TLK1 est un anticorps Lapin Polyclonal détectant TLK1 dans WB et ELISA. Adapté pour Humain et Rat.

Aperçu rapide pour TLK1 anticorps (C-Term) (ABIN6257779)

Antigène: TLK1 (Tousled-Like Kinase 1 (TLK1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TLK1 anticorps

Épitope: C-Term

Specificité: TLK1 Antibody detects endogenous levels of total TLK1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TLK1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TLK1

Antigène: TLK1 (Tousled-Like Kinase 1 (TLK1))

Autre désignation: TLK1

Sujet:

Description: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.

Gene: TLK1

Poids moléculaire: 87 kDa

ID gène: 9874

UniProt: Q9UKI8