CIRBP anticorps (C-Term)

N° du produit ABIN6257871

L’anticorps Lapin Polyclonal anti-CIRBP a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter CIRBP dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CIRBP anticorps (C-Term) (ABIN6257871)

Antigène: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIRBP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-CIRBP anticorps

Épitope: C-Term

Specificité: CIRBP Antibody detects endogenous levels of total CIRBP.

Homologie: Bovine,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CIRBP, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur CIRBP

Antigène: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Autre désignation: CIRBP

Sujet:

Description: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Gene: CIRBP

Poids moléculaire: 18 kDa

ID gène: 1153

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization