TRIO anticorps (Internal Region)

N° du produit ABIN6257891

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIO dans WB, ELISA, ICC, IF et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TRIO anticorps (Internal Region) (ABIN6257891)

Antigène: TRIO (Triple Functional Domain Protein (TRIO))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIO est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-TRIO anticorps

Épitope: Internal Region

Specificité: TRIO Antibody detects endogenous levels of total TRIO.

Homologie: Pig,Zebrafish,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TRIO, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TRIO

Antigène: TRIO (Triple Functional Domain Protein (TRIO))

Autre désignation: TRIO

Sujet:

Description: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity).

Gene: TRIO

Poids moléculaire: 31 kDa

ID gène: 7204

UniProt: O75962