APLP2 anticorps (C-Term)

N° du produit ABIN6257937

L’anticorps Lapin Polyclonal anti-APLP2 a été validé pour WB et ELISA. Il convient pour détecter APLP2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour APLP2 anticorps (C-Term) (ABIN6257937)

Antigène: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APLP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-APLP2 anticorps

Épitope: C-Term

Specificité: APLP2 Antibody detects endogenous levels of total APLP2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human APLP2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur APLP2

Antigène: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Autre désignation: APLP2

Sujet:

Description: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).

Gene: APLP2

Poids moléculaire: 87 kDa

ID gène: 334

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour