DDX20 anticorps (Internal Region)
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- Antigène Voir toutes DDX20 Anticorps
- DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DDX20 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- DDX20 Antibody detects endogenous levels of total DDX20.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human DDX20, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product DDX20 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))
- Autre désignation
- DDX20 (DDX20 Produits)
- Synonymes
- anticorps DDX20, anticorps DP103, anticorps GEMIN3, anticorps dp103, anticorps Dp103, anticorps si:dkey-193l3.3, anticorps wu:fb16g08, anticorps wu:fb59a11, anticorps DEAD-box helicase 20, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 20, anticorps DDX20, anticorps ddx20, anticorps Ddx20
- Sujet
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Description: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
Gene: DDX20
- Poids moléculaire
- 92 kDa
- ID gène
- 11218
- UniProt
- Q9UHI6
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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