LGR6 anticorps (Internal Region)

N° du produit ABIN6258202

Détail du produit anti-LGR6 anticorps

Antigène: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGR6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: LGR6 Antibody detects endogenous levels of total LGR6.

Homologie: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human LGR6, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur LGR6

Antigène: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Autre désignation: LGR6 (LGR6 Produits)

Synonymes: anticorps LGR6, anticorps GPCR, anticorps VTS20631, anticorps A530037C04Rik, anticorps D830026M09, anticorps RGD1560339, anticorps leucine rich repeat containing G protein-coupled receptor 6, anticorps leucine-rich repeat-containing G protein-coupled receptor 6, anticorps LGR6, anticorps Lgr6

Sujet:

Description: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

Gene: LGR6

Poids moléculaire: 104 kDa

ID gène: 59352

UniProt: Q9HBX8