OPRL1 anticorps (C-Term)
Aperçu rapide pour OPRL1 anticorps (C-Term) (ABIN6258295)
Antigène
Voir toutes OPRL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- OPRL1 Antibody detects endogenous levels of total OPRL1.
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Homologie
- Pig,Horse,Sheep,Dog
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human OPRL1, corresponding to a region within C-terminal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Date de péremption
- 12 months
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- OPRL1 (Opiate Receptor-Like 1 (OPRL1))
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Autre désignation
- OPRL1
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Sujet
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Description: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
Gene: OPRL1
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Poids moléculaire
- 41 kDa,
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ID gène
- 4987
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UniProt
- P41146
Antigène
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