PAEP anticorps
Aperçu rapide pour PAEP anticorps (ABIN6258298)
Antigène
Voir toutes PAEP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- PAEP antibody detects endogenous levels of total PAEP
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Réactivité croisée
- Humain, Rat (Rattus)
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PAEP (Progestagen-Associated Endometrial Protein (PAEP))
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Autre désignation
- PAEP
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Sujet
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Description: Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:9918684, PubMed:7531163). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155).
Gene: PAEP
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Poids moléculaire
- 21 kDa
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ID gène
- 5047
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UniProt
- P09466
Antigène
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