PHLDA3 anticorps (C-Term)
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- Antigène Voir toutes PHLDA3 Anticorps
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PHLDA3 est non-conjugé
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Application
- ELISA, Western Blotting (WB)
- Specificité
- PHLDA3 Antibody detects endogenous levels of total PHLDA3.
- Homologie
- Pig,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human PHLDA3, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PHLDA3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
- Autre désignation
- PHLDA3 (PHLDA3 Produits)
- Synonymes
- anticorps TIH1, anticorps Tih1, anticorps si:dz182n13.5, anticorps zgc:92333, anticorps pleckstrin homology like domain family A member 3, anticorps pleckstrin homology like domain, family A, member 3, anticorps pleckstrin homology-like domain, family A, member 3, anticorps PHLDA3, anticorps Phlda3, anticorps phlda3
- Sujet
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Description: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Gene: PHLDA3
- Poids moléculaire
- 14 kDa
- ID gène
- 23612
- UniProt
- Q9Y5J5
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