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PHLDA3 anticorps (C-Term)

PHLDA3 Reactivité: Humain, Souris, Rat ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258301
  • Antigène Voir toutes PHLDA3 Anticorps
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Épitope
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 21
    • 6
    • 6
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 18
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 19
    • 2
    Polyclonal
    Conjugué
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PHLDA3 est non-conjugé
    Application
    • 10
    • 8
    • 4
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Specificité
    PHLDA3 Antibody detects endogenous levels of total PHLDA3.
    Homologie
    Pig,Rabbit
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human PHLDA3, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PHLDA3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Autre désignation
    PHLDA3 (PHLDA3 Produits)
    Synonymes
    anticorps TIH1, anticorps Tih1, anticorps si:dz182n13.5, anticorps zgc:92333, anticorps pleckstrin homology like domain family A member 3, anticorps pleckstrin homology like domain, family A, member 3, anticorps pleckstrin homology-like domain, family A, member 3, anticorps PHLDA3, anticorps Phlda3, anticorps phlda3
    Sujet

    Description: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.

    Gene: PHLDA3

    Poids moléculaire
    14 kDa
    ID gène
    23612
    UniProt
    Q9Y5J5
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