Fibrinogen beta Chain anticorps (C-Term)

N° du produit ABIN6258456

Détail du produit anti-Fibrinogen beta Chain anticorps

Antigène: Fibrinogen beta Chain (FGB)

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrinogen beta Chain est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: FGB Antibody detects endogenous levels of total FGB.

Homologie: Zebrafish,Bovine,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human FGB, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Fibrinogen beta Chain

Antigène: Fibrinogen beta Chain (FGB)

Autre désignation: FGB (FGB Produits)

Synonymes: anticorps FGB, anticorps 2510049G14Rik, anticorps DKFZp470D0312, anticorps LOC100223598, anticorps fibrinogen, anticorps Ab1-216, anticorps Ac1-581, anticorps wu:fa55c11, anticorps zgc:77116, anticorps fgb, anticorps fibrinogen beta chain, anticorps fibrinogen beta chain L homeolog, anticorps FGB, anticorps Fgb, anticorps fgb, anticorps fgb.L

Sujet:

Description: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Gene: FGB

Poids moléculaire: 56 kDa

ID gène: 2244

UniProt: P02675