ARRDC3 anticorps (C-Term)

N° du produit ABIN6258500

Cet anticorps Lapin Polyclonal détecte spécifiquement ARRDC3 dans ELISA, WB, IF et ICC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ARRDC3 anticorps (C-Term) (ABIN6258500)

Antigène: ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARRDC3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-ARRDC3 anticorps

Épitope: C-Term

Specificité: ARRDC3 Antibody detects endogenous levels of total ARRDC3.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ARRDC3, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARRDC3

Antigène: ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))

Autre désignation: ARRDC3

Sujet:

Description: Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 (PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550).

Gene: ARRDC3

Poids moléculaire: 46 kDa

ID gène: 57561

UniProt: Q96B67