TTBK2 anticorps (C-Term)

N° du produit ABIN6258666

L’anticorps Lapin Polyclonal anti-TTBK2 a été validé pour WB et ELISA. Il convient pour détecter TTBK2 dans des échantillons de Humain et Souris.

Aperçu rapide pour TTBK2 anticorps (C-Term) (ABIN6258666)

Antigène: TTBK2 (tau Tubulin Kinase 2 (TTBK2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTBK2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TTBK2 anticorps

Épitope: C-Term

Specificité: TTBK2 Antibody detects endogenous levels of total TTBK2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TTBK2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TTBK2

Antigène: TTBK2 (tau Tubulin Kinase 2 (TTBK2))

Autre désignation: TTBK2

Sujet:

Description: Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro.

Gene: TTBK2

Poids moléculaire: 137 kDa

ID gène: 146057

UniProt: Q6IQ55