CDK5R1 anticorps (N-Term)

N° du produit ABIN6258750

Détail du produit anti-CDK5R1 anticorps

Antigène: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK5R1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CDK5R1/P35 Antibody detects endogenous levels of total CDK5R1/P35.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CDK5R1/P35, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CDK5R1

Antigène: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Autre désignation: CDK5R1 (CDK5R1 Produits)

Synonymes: anticorps CDK5P35, anticorps CDK5R, anticorps NCK5A, anticorps p23, anticorps p25, anticorps p35, anticorps p35nck5a, anticorps cdk5r1, anticorps zgc:92814, anticorps CDK5R1, anticorps Cdk5r, anticorps P25/P35, anticorps D11Bwg0379e, anticorps Xp35.1, anticorps cyclin dependent kinase 5 regulatory subunit 1, anticorps cyclin-dependent kinase 5, regulatory subunit 1b (p35), anticorps cyclin-dependent kinase 5 regulatory subunit 1, anticorps S100 calcium binding protein A9, anticorps cyclin-dependent kinase 5, regulatory subunit 1 (p35), anticorps cyclin-dependent kinase 5, regulatory subunit 1 (p35) L homeolog, anticorps CDK5R1, anticorps cdk5r1b, anticorps Cdk5r1, anticorps S100A9, anticorps cdk5r1.L

Classe de substances: Viral Protein

Sujet:

Description: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.

Gene: CDK5R1

Poids moléculaire: 38 kDa

ID gène: 8851

UniProt: Q15078

Pathways: Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity