ELOVL1 anticorps (Internal Region)

N° du produit ABIN6258770

Détail du produit anti-ELOVL1 anticorps

Antigène: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELOVL1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ELOVL1 Antibody detects endogenous levels of total ELOVL1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ELOVL1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ELOVL1

Antigène: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Autre désignation: ELOVL1 (ELOVL1 Produits)

Synonymes: anticorps AA407424, anticorps BB151133, anticorps Ssc1, anticorps elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1, anticorps ELOVL fatty acid elongase 1, anticorps Elovl1, anticorps ELOVL1

Sujet:

Description: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Gene: ELOVL1

Poids moléculaire: 35 kDa

ID gène: 64834

UniProt: Q9BW60