NOC2L anticorps (C-Term)

N° du produit ABIN6259130

Cet anticorps Lapin Polyclonal détecte spécifiquement NOC2L dans WB, ELISA, ICC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour NOC2L anticorps (C-Term) (ABIN6259130)

Antigène: NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOC2L est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-NOC2L anticorps

Épitope: C-Term

Specificité: NOC2L Antibody detects endogenous levels of total NOC2L.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NOC2L, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NOC2L

Antigène: NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))

Autre désignation: NOC2L

Sujet:

Description: Acts as an inhibitor of histone acetyltransferase activity, prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.

Gene: NOC2L

Poids moléculaire: 85 kDa

ID gène: 26155

UniProt: Q9Y3T9

Pathways: Negative Regulation of intrinsic apoptotic Signaling