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PPHLN1 anticorps (N-Term)

PPHLN1 Reactivité: Humain, Souris WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259270
  • Antigène Voir toutes PPHLN1 Anticorps
    PPHLN1 (Periphilin 1 (PPHLN1))
    Épitope
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 27
    • 21
    • 16
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 25
    • 3
    Lapin
    Clonalité
    • 26
    • 2
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PPHLN1 est non-conjugé
    Application
    • 28
    • 13
    • 13
    • 8
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    PPHLN Antibody detects endogenous levels of total PPHLN.
    Homologie
    Pig,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human PPHLN, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PPHLN1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    PPHLN1 (Periphilin 1 (PPHLN1))
    Autre désignation
    PPHLN1 (PPHLN1 Produits)
    Synonymes
    anticorps MGC75908, anticorps MGC81987, anticorps wu:fb83c09, anticorps zgc:158246, anticorps si:ch211-155a11.2, anticorps HSPC232, anticorps 1110063K05Rik, anticorps 1600022A19Rik, anticorps CR, anticorps HSPC206, anticorps periphilin 1, anticorps periphilin 1 S homeolog, anticorps PPHLN1, anticorps pphln1, anticorps pphln1.S, anticorps Pphln1
    Sujet

    Description: Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Probable).

    Gene: PPHLN1

    Poids moléculaire
    53 kDa
    ID gène
    51535
    UniProt
    Q8NEY8
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