Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

RFTN1 anticorps (Internal Region)

RFTN1 Reactivité: Humain, Souris WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259466
  • Antigène Voir toutes RFTN1 Anticorps
    RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 8
    • 4
    • 3
    • 1
    Humain, Souris
    Hôte
    • 9
    Lapin
    Clonalité
    • 9
    Polyclonal
    Conjugué
    • 9
    Cet anticorp RFTN1 est non-conjugé
    Application
    • 9
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    RFTN1 Antibody detects endogenous levels of total RFTN1.
    Homologie
    Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human RFTN1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RFTN1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
    Autre désignation
    RFTN1 (RFTN1 Produits)
    Synonymes
    anticorps RAFTLIN, anticorps RGD1310777, anticorps RGD1563347, anticorps 2310015n21rik, anticorps mig2, anticorps pig9, anticorps pib10, anticorps raftlin, anticorps DKFZp459B0154, anticorps 2310015N21Rik, anticorps AI853526, anticorps PIB10, anticorps PIG9, anticorps raftlin, lipid raft linker 1, anticorps raftlin lipid raft linker 1, anticorps RFTN1, anticorps Rftn1, anticorps rftn1
    Sujet

    Description: Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216).

    Gene: RFTN1

    Poids moléculaire
    63 kDa
    ID gène
    23180
    UniProt
    Q14699
Vous êtes ici:
Support technique