SRRM1 anticorps (C-Term)

N° du produit ABIN6259480

Détail du produit anti-SRRM1 anticorps

Antigène: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Épitope: C-Term

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRRM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: SRRM1 Antibody detects endogenous levels of total SRRM1.

Homologie: Pig,Bovine,Horse,Rabbit,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SRRM1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur SRRM1

Antigène: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Autre désignation: SRRM1 (SRRM1 Produits)

Synonymes: anticorps 160-KD, anticorps POP101, anticorps SRM160, anticorps AA407769, anticorps Srm160, anticorps serine and arginine repetitive matrix 1, anticorps serine/arginine repetitive matrix 1, anticorps SRRM1, anticorps Srrm1

Sujet:

Description: Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.

Gene: SRRM1

Poids moléculaire: 102 kDa

ID gène: 10250

UniProt: Q8IYB3