WEE2 anticorps (Internal Region)

N° du produit ABIN6259536

L’anticorps anti-WEE2 Polyclonal Lapin est utilisé pour la détection de WEE2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ICC et IF.

Aperçu rapide pour WEE2 anticorps (Internal Region) (ABIN6259536)

Antigène: WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WEE2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-WEE2 anticorps

Épitope: Internal Region

Fonction: WEE2 Antibody

Specificité: WEE2 Antibody detects endogenous levels of total WEE2

Homologie: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human WEE2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur WEE2

Antigène: WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))

Autre désignation: WEE2

Sujet:

Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

Gene: WEE2

Poids moléculaire: 60 kDa

ID gène: 494551

UniProt: P0C1S8

Pathways: M Phase