AFG3L2 anticorps (C-Term)

N° du produit ABIN6259816

Détail du produit anti-AFG3L2 anticorps

Antigène: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFG3L2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: AFG3L2 Antibody detects endogenous levels of total AFG3L2.

Homologie: Pig,Bovine,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human AFG3L2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur AFG3L2

Antigène: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Autre désignation: AFG3L2 (AFG3L2 Produits)

Synonymes: anticorps MGC147390, anticorps si:ch211-12e1.4, anticorps SCA28, anticorps SPAX5, anticorps 2310036I02Rik, anticorps AW260507, anticorps Emv66, anticorps par, anticorps AFG3 like matrix AAA peptidase subunit 2, anticorps AFG3-like protein 2, anticorps AFG3 ATPase family gene 3-like 2 (S. cerevisiae), anticorps AFG3-like AAA ATPase 2, anticorps AFG3-like AAA ATPase 2 L homeolog, anticorps AFG3L2, anticorps LOC578526, anticorps afg3l2, anticorps afg3l2.L, anticorps Afg3l2

Sujet:

Description: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).

Gene: AFG3L2

Poids moléculaire: 80-90 kDa

ID gène: 10939

UniProt: Q9Y4W6

Pathways: Skeletal Muscle Fiber Development