AGO1 anticorps (Internal Region)

N° du produit ABIN6259824

Détail du produit anti-AGO1 anticorps

Antigène: AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGO1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: AGO1 Antibody detects endogenous levels of total AGO1.

Homologie: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human AGO1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur AGO1

Antigène: AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))

Autre désignation: AGO1 (EIF2C1 Produits)

Synonymes: anticorps Ago, anticorps Ago-1, anticorps Ago1, anticorps CG6671, anticorps Dm Ago1, anticorps Dmel\\CG6671, anticorps MRE20, anticorps ago1, anticorps ago1-1, anticorps anon-WO0257455.29, anticorps dAGO1, anticorps dAgo1, anticorps l(2)04845, anticorps l(2)4845, anticorps l(2)k00208, anticorps l(2)k08121, anticorps GB12654, anticorps dsim_GLEANR_9718, anticorps DsimGD25729, anticorps GD25729, anticorps EIF2C1, anticorps EIF2C, anticorps GERP95, anticorps Q99, anticorps Eif2c1, anticorps ARGONAUTE 1, anticorps T1N15.2, anticorps T1N15_2, anticorps Argonaute-1, anticorps protein argonaute-2, anticorps argonaute 1, anticorps Argonaute 1, anticorps protein argonaute-1, anticorps argonaute 1, RISC catalytic component, anticorps argonaute RISC catalytic subunit 1, anticorps Stabilizer of iron transporter SufD / Polynucleotidyl transferase, anticorps AGO1, anticorps LOC552062, anticorps ago1, anticorps LOC659936, anticorps Dsim\AGO1, anticorps Ago1, anticorps LOC100386910, anticorps LOC100482671, anticorps LOC475337

Sujet:

Description: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).

Gene: AGO1

Poids moléculaire: 110 kDa

ID gène: 26523

UniProt: Q9UL18

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Transport, Regulation of Actin Filament Polymerization, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization