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AKR1C4 anticorps

L’anticorps Lapin Polyclonal anti-AKR1C4 a été validé pour WB, ELISA et IHC. Il convient pour détecter AKR1C4 dans des échantillons de Humain et Rat.
N° du produit ABIN6259863

Aperçu rapide pour AKR1C4 anticorps (ABIN6259863)

Antigène

Voir toutes AKR1C4 Anticorps
AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reactivité

  • 31
  • 9
  • 2
Humain, Rat

Hôte

  • 24
  • 5
  • 1
  • 1
Lapin

Clonalité

  • 29
  • 2
Polyclonal

Conjugué

  • 18
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp AKR1C4 est non-conjugé

Application

  • 23
  • 14
  • 6
  • 4
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Specificité

    AKR1C4 Antibody detects endogenous levels of total AKR1C4

     Réactivité croisée

    Humain, Rat (Rattus)

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogène

    A synthesized peptide derived from human AKR1C4

    Isotype

    IgG
  • Indications d'application

    WB 1:1000-3000 IHC 1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C.Stable for 12 months from date of receipt

    Date de péremption

    12 months
  • Antigène

    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

    Autre désignation

    AKR1C4

    Sujet

    Description: Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

    Gene: AKR1C4

    Poids moléculaire

    37 kDa

    ID gène

    1109

    UniProt

    P17516

    Pathways

    Steroid Hormone Biosynthesis
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