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AKR1C4 anticorps

AKR1C4 Reactivité: Humain, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259863
  • Antigène Voir toutes AKR1C4 Anticorps
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Reactivité
    • 35
    • 9
    • 2
    Humain, Rat
    Hôte
    • 28
    • 5
    • 1
    • 1
    Lapin
    Clonalité
    • 33
    • 2
    Polyclonal
    Conjugué
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AKR1C4 est non-conjugé
    Application
    • 27
    • 18
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    AKR1C4 Antibody detects endogenous levels of total AKR1C4
     Réactivité croisée
    Humain, Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human AKR1C4
    Isotype
    IgG
    Top Product
    Discover our top product AKR1C4 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000 IHC 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Autre désignation
    AKR1C4 (AKR1C4 Produits)
    Synonymes
    anticorps 3-alpha-HSD, anticorps C11, anticorps CDR, anticorps CHDR, anticorps DD-4, anticorps DD4, anticorps HAKRA, anticorps aldo-keto reductase family 1 member C4, anticorps AKR1C4
    Sujet

    Description: Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

    Gene: AKR1C4

    Poids moléculaire
    37 kDa
    ID gène
    1109
    UniProt
    P17516
    Pathways
    Steroid Hormone Biosynthesis
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