APOBEC3A/B anticorps (Internal Region)

N° du produit ABIN6259985

Cet anticorps Lapin Polyclonal détecte spécifiquement APOBEC3A/B dans IHC et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour APOBEC3A/B anticorps (Internal Region) (ABIN6259985)

Antigène: APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-APOBEC3A/B anticorps

Épitope: Internal Region

Fonction: APOBEC3A/B Antibody

Specificité: APOBEC3A/B Antibody detects endogenous levels of total APOBEC3A/B

Homologie: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human APOBEC3A/B, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur APOBEC3A/B

Antigène: APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))

Autre désignation: APOBEC3A/B

Sujet:

Description: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

Gene: APOBEC3A

Poids moléculaire: 23 kDa,46 kDa

ID gène: 100, 913, 187

UniProt: P31941