APOBEC3A/B anticorps

N° du produit ABIN6259985

Détail du produit anti-APOBEC3A/B anticorps

Antigène: APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOBEC3A/B est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: APOBEC3A/B Antibody detects endogenous levels of total APOBEC3A/B

Réactivité croisée: Humain

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human APOBEC3A/B

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur APOBEC3A/B

Antigène: APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))

Autre désignation: APOBEC3A/B (APOBEC3A_B Produits)

Synonymes: anticorps A3A, anticorps APOBEC3A and APOBEC3B deletion hybrid, anticorps APOBEC3A_B

Sujet:

Description: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

Gene: APOBEC3A

Poids moléculaire: 23 kDa,46 kDa

ID gène: 100, 913, 187

UniProt: P31941, Q9UH17