ARL3 anticorps (C-Term)

N° du produit ABIN6260040

L’anticorps Lapin Polyclonal anti-ARL3 a été validé pour WB. Il convient pour détecter ARL3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ARL3 anticorps (C-Term) (ABIN6260040)

Antigène: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ARL3 anticorps

Épitope: C-Term

Specificité: ARL3 Antibody detects endogenous levels of total ARL3.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ARL3, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARL3

Antigène: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Autre désignation: ARL3

Sujet:

Description: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.

Gene: ARL3

Poids moléculaire: 20 kDa

ID gène: 403

UniProt: P36405