PYDC1 anticorps
Aperçu rapide pour PYDC1 anticorps (ABIN6260072)
Antigène
Voir toutes PYDC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- ASC2 Antibody detects endogenous levels of total ASC2
-
Réactivité croisée
- Humain, Souris, Rat (Rattus)
-
Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogène
- A synthesized peptide derived from human ASC2
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:1000-3000 IHC 1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
-
Date de péremption
- 12 months
-
-
- PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
-
Autre désignation
- ASC2
-
Sujet
-
Description: Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.
Gene: PYDC1
-
Poids moléculaire
- 10 kDa
-
ID gène
- 260434
-
UniProt
- Q8WXC3
Antigène
-