BRAP anticorps (C-Term)

N° du produit ABIN6260302

Détail du produit anti-BRAP anticorps

Antigène: BRAP (BRCA1 Associated Protein (BRAP))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRAP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: BRAP Antibody detects endogenous levels of total BRAP.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human BRAP, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur BRAP

Antigène: BRAP (BRCA1 Associated Protein (BRAP))

Autre désignation: BRAP (BRAP Produits)

Synonymes: anticorps imp, anticorps MGC68778, anticorps zgc:92894, anticorps BRAP, anticorps BRAP2, anticorps IMP, anticorps RNF52, anticorps 3010002G07Rik, anticorps BRCA1 associated protein S homeolog, anticorps BRCA1 associated protein, anticorps BRCA1-associated protein, anticorps brca1-associated protein, anticorps brap.S, anticorps brap, anticorps BRAP, anticorps NAEGRDRAFT_81654, anticorps CC1G_00971, anticorps CpipJ_CPIJ003557, anticorps Tsp_05101, anticorps LOC100282389, anticorps Brap

Sujet:

Description: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Gene: BRAP

Poids moléculaire: 67 kDa

ID gène: 8315

UniProt: Q7Z569